Deep Brain Stimulation Influences Brain Structure in Alzheimer's Disease

O10: Deep Brain Stimulation and Psychiatry

The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...

deep brain stimulation and gene expression alterations in parkinson’s disease

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Deep Brain Stimulation and Gene Expression Alterations in Parkinson’s Disease

Deep Brain Stimulation in Parkinson’s Disease

In some regards, the surgical procedures for the different targets are similar. The target can be located using a combination of imaging (MRI, C T, ventriculography, depending on the centre) and electrophysiology (electrical stimulation and, in some centres, microrecordings). Implantation of the electrode is generally performed under local anaesthesia to allow the evaluation of the effect of th...

Adaptive deep brain stimulation in Parkinson's disease

Although Deep Brain Stimulation (DBS) is an established treatment for Parkinson's disease (PD), there are still limitations in terms of effectivity, side-effects and battery consumption. One of the reasons for this may be that not only pathological but also physiological neural activity can be suppressed whilst stimulating. For this reason, adaptive DBS (aDBS), where stimulation is applied acco...